Saturday, July 22, 2017

Calamine Skin Lotion Sample Preparation: without Kaolin + Glycerin

Calamine Lotion USP

1. Formulation 

Calamine ..........................................................80mg
Glycerin ...........................................................80mg
Bentonite Magma.............................................20mL
Calcium Hydroxide Topical Solution.............qs 1.000mL

2. Procedure

Dilute the bentonite magma with an equal volume of calcium hydroxide topical solution. Mix the powder intimately with the glycerin and about 100mL of the diluted magma, triturating until a smooth, uniform paste is formed. Gradually incorporate the remainder of the diluted magma. Finally add enough calcium hydroxide topical solution to make 1000mL, and shake well. If more viscous consistency in the lotion desired, the quantity of bentonite magma may be increased to not more than 400mL. 



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