A new treatment against diabetes: Apelin

Apelin has been functioned as a regulator of insulin then our body is able to produce whereby stimulating cells to consume the glucose from the vessel. Results published in obesity and metabolism.

1048 institute with of metabolic and cardiovascular disease Inserm University Toulouse III-Paul Sabatier investigated a clinical trial to resume the function and effectiveness of apelin in the body control and palliative with blood sugar by the sensitivity of host cells.

Apelin was found to exist in the whole body and able to regulate blood sugar by stimulating sensitive cells whose responsible to stock and regulate the threshold of glucose in the blood.  According the research, the molecule plays the role when the principle function of sugar regulation isn't weakened. 

The phase 1 clinical trial was leaded with 16 healthy persons with obesity randomly separated into two groups with two different dosage by intravenous administration. Namely 9nmol/kg first group and 30nmol/kg second group. 

In sum, patients who received low dose promise a good result while whom received high dose showed a great sensitivity to the target cells. Both result doesn't show side effects. 

Conclusion, researchers predict to get more volunteers to pass through next clinical stage and approve a good confirmation of the new therapies.

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